THE INTERNET IS THINKING
Earlier sources: Science
Science investigates the natural world through observation, experiments, and mathematical models. Explore papers and developments in biology, medicine, materials, neuroscience, physics, climate, and mathematics; a reported finding is not necessarily established consensus.
SYMTRI organizes observations from public sources into a living map. Connections reflect shared subject matter; they do not establish causation or endorse a source.
Open in the map ↗1325 classified signals in the fourteen-day window. Recent momentum: steady. These counts include signals awaiting readable evidence.
Earlier sources
Up to ten sources with readable evidence, ordered by their feed timestamp. These archive sources can be older than the live fourteen-day window. This list is a sample, not a measure of total activity. Dates distinguish paper publication, repository creation, model/dataset activity, Hacker News posts, and KEV catalog additions. “First archived” records when SYMTRI first stored the signal.
- Europe PMC · Published · First archived
GALC variants affect Glucocerebrosidase to Galactosylceramidase activity ratio ↗
Objective: Genes within the lysosomal glycosphingolipid pathway, including GBA1 and GALC, are important genetic risk factors in Parkinson's disease (PD). We hypothesized that PD risk relates not only to individual enzyme effects but also to coordination between glucocerebrosidase (GCase) and galactosylceramidase (GalCase) activities, and examined how genetic variants influence their activity ratio. Methods: We studied 1,290 individuals from the Parkinson's Precision Medicine Initiative and Columbia University cohorts with genetic and dried-blood-spot enzymatic data. Genome-wide association ana
- Europe PMC · Published · First archived
Does gut microbial richness lost with industrialisation matter for infection? A two-direction test in Gambian toddlers ↗
Background: and objectives: Industrialisation is associated with lower gut microbial richness. The ecological insurance hypothesis proposes that richer communities buffer disturbance via overlapping functions, possibly affecting infection susceptibility. We state predictions, audit the evidence, and test the richness-infection relationship in Gambian children. Methodology: We analysed 452 children aged 6-35 months with Day 85 stool 16S profiles and dated infections over 113 days. Diversity used Hill numbers (q = 0, 1, 2); redundancy was inferred from reference-genome gene content. We examined
- Europe PMC · Published · First archived
Dissociable neural oscillations track subjective value under risk and ambiguity ↗
How the brain values uncertain prospects and translates them into choices is a central question in decision neuroscience. Current accounts propose that decisions under risk and ambiguity share a valuation process that integrates outcome with probability information, with ambiguity additionally requiring evaluation of the uncertainty about the probabilities themselves. Here we used computational modeling to estimate trial-wise subjective value and tested whether it was tracked by shared or distinct neural dynamics under risk and ambiguity. Participants accepted or rejected risky and ambiguous m
- Europe PMC · Published · First archived
A multidimensional normative database of experiential ratings for German nouns ↗
Theories of semantic representation propose that concepts are grounded in multiple forms of experience, yet normative resources capturing this multidimensionality remain scarce, especially in German. We present a database of experiential ratings for 1,985 German nouns, with particularly broad coverage of abstract concepts (a 3:1 ratio of abstract to concrete nouns). In total, 354 native German speakers rated the extent to which the meaning of each word is associated with 16 experiential dimensions spanning perceptual, motor, affective, cognitive, social and magnitude-related domains, complemen
- Europe PMC · Published · First archived
Neuroscience-Informed Psychoeducation for Anxiety: Translating Brain–Behavior Models into Scalable Clinical Tools ↗
Advances in affective and systems neuroscience have clarified how distributed brain networks encode threat processing, generate bodily arousal, and shape cognitive and behavioral features of anxiety disorders. However, this progress has not been systematically translated into patient-facing educational tools or clinical care. Neuroscience-Informed Psychoeducation (NIPE) extends conventional psychoeducation by incorporating brain-based explanations of symptoms and treatment, while also structuring materials to engage attention, memory, and self-referential processing. Emerging work suggests NIP
- Europe PMC · Published · First archived
Genetic Variation Disrupts RNA Structural Repression of Cryptic Splice Sites ↗
Abstract Interpreting how genetic variants alter RNA processing remains a major challenge in human genetics. Using Framingham Heart Study data and genome-wide and mutational analyses, we show that G-tract-disrupting variants activate cryptic 3′ splice sites in association with predicted local RNA structural destabilization, while compensatory mutations restoring structural stability re-establish splicing repression. Approximately 1.6 million such sites occur genome-wide, revealing RNA structural disruption as a candidate mechanism of variant-induced cryptic splicing.
- Europe PMC · Published · First archived
Genome-wide identification and annotation of genetic variants in captive white Bengal tigers in Bangladesh: a genomic resource for conservation genetics ↗
Abstract The integration of state-of-the-art molecular techniques with conventional breeding tools is essential for optimizing selection and breeding management in captive wildlife populations. Despite decades of research, a comprehensive catalogue of genetic variation in Bengal tigers ( Panthera tigris tigris ) in Bangladesh has been lacking, as most previous work has been descriptive. This study aimed to characterize the genome of captive white Bengal tigers to establish a catalogue of genetic variants as a resource for future studies of predatory traits, inbreeding depression, and genetic l
- Europe PMC · Published · First archived
Comparative genome and protein analysis of Deinococcus radiodurans on heavy metal and radiation resistance ↗
Abstract D.radiodurans is robust bacteria that carry an extraordinary DNA repair system. The presence of multiple components distributed on the chromosomes and megaplasmid enables them to survive in a variety of environments under conditions of starvation, oxidative stress, and high amounts of DNA damage. Although recent developments in genes and genomic sequencing have significantly increased our knowledge of microbes, studies on the D. radiodurans R1 DSM 20539T using an integrated comparative genomics approach are scarce. So the study aims to analyze the genome and proteome of the D. radiodu
- arXiv · Published · First archived
Numerical error analysis of EMC3-EIRENE simulations in the HSX stellarator ↗
Plasma edge simulations with codes like EMC3-EIRENE are widely used to study fusion magnetic confinement devices. However, numerical errors can significantly impact the simulation solution and are often insufficiently characterized. These errors consist of the statistical error, bias, and time integration error, resulting from the finite sampling and tracking of Monte Carlo particles, and the discretization error, resulting from a finite grid resolution. This work presents the first comprehensive numerical error analysis of EMC3-EIRENE simulations in stellarator geometries, focusing on edge pl…
- arXiv · Published · First archived
Similar evapotranspiration responses mask contrasting modes of water access during drought in California ↗
Atmospheric warming raises evaporative demand, but actual evapotranspiration (ETa) may track demand or decouple under water limitation. Here, we quantified demand-tracking ability from regression slopes relating deseasonalized ETa and reference evapotranspiration (ETo) anomalies across California during 2008-2024. Forests and croplands retained similar positive tracking under severe drought, whereas grasslands and shrublands showed weak or negative responses. Despite similar demand tracking, forest responses were consistent with subsurface-storage access, whereas cropland responses reflected m…
Live window recorded . This is the ingestion observation time, not the publication or discovery date of each source.
How to assess evidence about Science
Check each original source for its methods, release status, limitations, and supporting data. A repository announcement, a preprint, and a published study provide different kinds of evidence. SYMTRI’s subject classification helps discovery; it does not independently validate the source’s claims.
See the collection and counting methodology ↗ · Read the weekly synthesis ↗
Follow a thread
Explore related regions
These navigation suggestions are part of the map’s editorial structure, rather than measured evidence of a connection.