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Earlier sources: Science
Science investigates the natural world through observation, experiments, and mathematical models. Explore papers and developments in biology, medicine, materials, neuroscience, physics, climate, and mathematics; a reported finding is not necessarily established consensus.
SYMTRI organizes observations from public sources into a living map. Connections reflect shared subject matter; they do not establish causation or endorse a source.
Open in the map ↗1595 classified signals in the fourteen-day window. Recent momentum: steady. These counts include signals awaiting readable evidence.
Earlier sources
Up to ten sources with readable evidence, ordered by their feed timestamp. These archive sources can be older than the live fourteen-day window. This list is a sample, not a measure of total activity. Dates distinguish paper publication, repository creation, model/dataset activity, Hacker News posts, and KEV catalog additions. “First archived” records when SYMTRI first stored the signal.
- OpenAlex · Published · First archived
Genome-wide analysis of genetic modifiers of Crohn’s disease and ulcerative colitis risk in response to tobacco smoking ↗
Background Gene-environment interactions (GxE) are fundamental for understanding the mechanisms of human diseases. Tobacco smoking is of particular interest for Inflammatory bowel disease (IBD), as it worsens Crohn's disease (CD) but protects against ulcerative colitis (UC). Here, we systematically examined the genome-wide genetic modifiers of tobacco smoking and analysed functional smoking-dependent expression quantitative trait loci (eQTL) in IBD intestinal tissues. Methods Multiplicative interaction effects of genetic variants and tobacco smoking were estimated and meta-analysed from two in…
- OpenAlex · Published · First archived
Caenorhabditis elegans small heat-shock protein HSP-12.6 has a highly specialized protective function towards muscle thick filaments in vivo ↗
Small heat-shock proteins (sHSPs) are an ancient and diverse class of molecular chaperones, acting as a first line of defence against proteotoxic stresses. While the canonical sHSPs prevent uncontrollable aggregation of a broad range of non-native substrates, a subset of sHSPs do not exhibit this broad activity in vitro, and their functions in vivo are poorly understood. Interestingly, several such sHSPs are selectively expressed in muscle tissues, including by myogenic programmes, indicating probable functional roles. We examined in vivo function of Caenorhabditis elegans HSP-12.6, which poss…
- OpenAlex · Published · First archived
Physics-informed Graph Attention-Transformer networks for multi-scale residual displacement prediction in progressive collapse of RC frames ↗
Nonlinear dynamic finite element analysis (FEA) is the mainstream method for assessing progressive collapse of structures, but its prohibitive computational cost limits rapid evaluation of damaged building systems. This paper proposes a physics-informed Graph Attention-Transformer (GAT-Transformer) framework as an engineering informatics surrogate for predicting residual displacements of reinforced concrete (RC) frames under progressive collapse. The framework transforms structural layouts, initial column-removal scenarios, and physical attributes into graph-based representations, in which bea…
- OpenAlex · Published · First archived
Draft genome sequence of Acinetobacter soli CELK8 isolated from the taro ( Colocasia esculenta ) rhizosphere ↗
CELK8, isolated from the taro rhizosphere in Bangladesh, revealed a 3,478,463 bp genome assembled into 126 contigs with 43.0% GC content and 126.5× coverage. Genome analysis predicted genes linked to plant growth-promoting (PGP) traits and biosynthetic gene clusters, highlighting its multi-trait PGP potential.
- OpenAlex · Published · First archived
Peptide-protein interactions in drug discovery ↗
Peptide-protein interactions are emerging as a major focus in drug discovery because they underpin many biological processes and provide a powerful means to modulate protein-protein interactions (PPIs), including targets long considered "undruggable." Peptide therapeutics occupy a unique middle ground between small molecules and biologics, combining high target selectivity with structural and functional versatility. This review integrates experimental and computational perspectives, summarizing current strategies for peptide ligand discovery, AI-based modeling, and generative peptide design. W…
- OpenAlex · Published · First archived
Recoverable quantum computation: An information-centric paradigm for quantum computing with errors ↗
Quantum computing promises transformative advances in computation, communication, sensing, and machine learning. Yet, the realization of large-scale fault-tolerant quantum computers remains hindered by the enormous overhead required for quantum error correction. This challenge raises a fundamental question: Must useful quantum computing wait until fully fault-tolerant quantum hardware becomes available? In this Perspective, we propose recoverable quantum computation (RQC), an information-centric paradigm for quantum computing with errors. Rather than requiring faithful preservation of the comp…
- OpenAlex · Published · First archived
Conversion of DNA Copy Number Ratios to Mass Fractions for Quantifying Chicken Adulteration in Duck Meat by Digital PCR ↗
Meat adulteration, particularly the substitution of duck with chicken, threatens food authenticity, consumer trust, and regulatory compliance. However, converting DNA copy number measurements into meat mass fractions remains challenging. This study developed a digital PCR (dPCR)-based quantitative for determining chicken in duck. Singleplex and duplex dPCR assays targeting single-copy nuclear genes specific to chicken, duck and the conserved myostatin gene were developed and optimized. Five sets of binary chicken-in-duck mixtures were prepared and analyzed across 0–100% (w/w) to account for bi…
- OpenAlex · Published · First archived
Development of ultrafast and radiation-hard GAGG for the next-generation of High-Energy Physics calorimeters ↗
The evolution of High Energy Physics (HEP) toward future collider experiments with High Luminosity (HL), such as the HL-LHC, requires the development of scintillating materials that combine high density, excellent radiation hardness and an ultrafast response. While Cerium-doped Gadolinium Aluminum Gallium Garnet (GAGG:Ce) offers a very high light yield and resilience to irradiation, its typical decay time of approximately 50–60 ns may lead to pile-up effects in high-rate environments. In this paper, we report on the development and multi-stage characterization of various accelerated GAGG compo…
- OpenAlex · Published · First archived
Granthi: Higher-Order Quantum Programming via Unitary Wiring ↗
Existing quantum programming languages confine higher-order structure to a classical host while restricting the quantum layer to first-order operations on qubits. This paper presents Granthi, a purely unitary higher-order quantum programming language built on three design commitments: quantum programs are first-class values that may be passed, returned, and coherently composed; additive structure is tag-preserving routing rather than observational branching, so control may remain in superposition; and programmer-facing finite label types with named reversible operations provide domain-level co…
- OpenAlex · Published · First archived
LLM-driven design of physics-constrained constitutive models: Two agents are better than one ↗
Abstract Developing constitutive models that capture how materials deform under load traditionally requires years of specialized expertise in continuum mechanics, machine learning, and scientific programming. Large language models (LLMs) have recently been shown to lower this barrier by generating constitutive models on demand, but existing single-agent pipelines lack systematic checks that the resulting models respect fundamental physical laws. To close this gap, we introduce the first multi-agent LLM-driven approach for constitutive model generation: a Creator agent proposes a model tailored…
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Check each original source for its methods, release status, limitations, and supporting data. A repository announcement, a preprint, and a published study provide different kinds of evidence. SYMTRI’s subject classification helps discovery; it does not independently validate the source’s claims.
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