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Earlier sources: Science
Science investigates the natural world through observation, experiments, and mathematical models. Explore papers and developments in biology, medicine, materials, neuroscience, physics, climate, and mathematics; a reported finding is not necessarily established consensus.
SYMTRI organizes observations from public sources into a living map. Connections reflect shared subject matter; they do not establish causation or endorse a source.
Open in the map ↗1709 classified signals in the fourteen-day window. Recent momentum: steady. These counts include signals awaiting readable evidence.
Earlier sources
Up to ten sources with readable evidence, ordered by their feed timestamp. These archive sources can be older than the live fourteen-day window. This list is a sample, not a measure of total activity. Dates distinguish paper publication, repository creation, model/dataset activity, Hacker News posts, and KEV catalog additions. “First archived” records when SYMTRI first stored the signal.
- Europe PMC · Published · First archived
Complete genome sequence of Salmonella enterica subsp. houtenae from the oral cavity of a diseased blue-tongued lizard ( Tiliqua sp.). ↗
A Salmonella enterica strain BT from the oral cavity of a diseased blue-tongued lizard was sequenced on the Oxford Nanopore platform. The assembled 4.8 Mbp genome consists of one circular chromosome and one circular plasmid (pBT). In silico serotyping suggested a rare serovar 40:z 4 ,z 23 :- of the subspecies houtenae (IV).
- Europe PMC · Published · First archived
Draft genome sequence of a multidrug-resistant Streptococcus gallolyticus strain MTR-Sg-DF01 isolated from an apparently healthy domestic duck. ↗
We report the draft genome sequence of a multidrug-resistant Streptococcus gallolyticus strain MTR-Sg-DF01, isolated from the feces of an apparently healthy duck. The 2.05-Mb genome harbored the resistance genes qac G, van T, and van Y, but lacked plasmids, and encoded a Bovicin 255 biosynthetic cluster, highlighting its relevance to zoonotic AMR surveillance.
- Europe PMC · Published · First archived
Genome mining and metabolomics reveal context-dependent biosynthetic potential in a core poplar dark septate endophyte. ↗
Dark septate endophytes (DSEs) are ubiquitous root-colonizing fungi characterized by melanized, septate hyphae and a frequent association with plants in stressful or nutrient-poor environments. Although DSEs are increasingly recognized for context-dependent effects on host stress resilience, the specialized metabolic capacity of many DSE lineages remains poorly resolved. Hyaloscypha finlandica is a recurrent root-associated fungus of Populus and other hosts, making it a useful system for understanding symbiotic mechanisms using multi-omics analyses. Here, we combined comparative biosynthetic g
- Europe PMC · Published · First archived
Influence of Hypothermia on Triggering of Malignant Hyperthermia in a Mouse Model Expressing Type I Ryanodine Receptor-p.R2509C. ↗
Background Although hyperthermia exacerbates the pathophysiology of malignant hyperthermia (MH), the response to hypothermia remains poorly understood. MH susceptible-swine studies suggested that hypothermia prevents MH, yet clinical cases occur during hypothermic cardiopulmonary bypass. This study aimed to elucidate whether hypothermia inhibits the MH trigger or merely decelerates the progression of the lethal metabolic cascade. Methods Pharmacological sensitivity of type 1 ryanodine receptor was evaluated in myotubes from heterozygous p.R2509C knock-in mice and wild-type (WT) mice by measuri
- Europe PMC · Published · First archived
Engineered Extracellular Vesicle Revitalizing Macrophage Energy Metabolism for Aged Wound Repair. ↗
One major obstacle for aged wound healing is the abnormal senescence of macrophages in chronic wounds which causes immunosenescence. Tissue homeostasis depends on regulation of metabolism in accumulating senescent cells (SnCs) with aging, and cell activation for aged tissue repair requires sufficient energy. Therapeutic advancements are potential by employing metabolic strategies for intervention. First, a disorder of arginine-oxidative phosphorylation metabolism in aging skin was found, which may be the main culprit of aging. Engineered EVs (4-octyl itaconate (4OI)-EVs) which possess naturall
- Europe PMC · Published · First archived
Evidence of parental care as a newly identified reproductive isolating barrier. ↗
Variation in behaviour can contribute to reproductive isolation by preventing gene flow among populations. Here, we tested the novel hypothesis that parental care, when dysregulated, can function as a reproductive isolating mechanism in three-spined stickleback fish (Gasterosteus aculeatus). In the typical 'common' stickleback ecotype, males provide care to their offspring by fanning with their pectoral fins and defending their nest. By contrast, a divergent 'white' stickleback ecotype has evolutionarily lost care and disperses embryos into the surrounding environment. We examined how paternal
- arXiv · Published · First archived
The Localized 12-hour Wave Over Alaska: Leveraging Meridional Wind Measurements From the Sodium Lidar ↗
The 12-h wave in meridional winds in the mesosphere and lower thermosphere (MLT) during the solar minimum 2018-2019 Arctic winter is investigated using sodium lidar observations at Poker Flat Research Range (PFRR), Chatanika, Alaska (64N,147W). Nightly 12-h wave amplitudes increased significantly during December-January, with amplitudes exceeding 130 m/s above 97 km on several days. This was more than double the 12-h wave amplitudes observed outside this time period. Meteor radar winds over Chatanika also showed significant increase in meridional wind 12-h wave amplitudes at altitudes between…
- arXiv · Published · First archived
PR-Smoother: Simulator-Preserving Non-Gaussian Smoothing for Data Assimilation ↗
Many physical data assimilation (DA) workflows require smoothing methods that represent non-Gaussian posteriors over physical state variables, scale to high-dimensional simulators, train from observation windows alone, and remain compatible with calibration of the prescribed simulator. We introduce PR-Smoother, a simulator-preserving amortized smoother designed for this prescribed-simulator DA regime. Its key design principle is to keep the prescribed simulator explicit in both the evidence lower bound and the variational family: rather than learning replacement dynamics or a learned trajector…
- arXiv · Published · First archived
Analysis of trade-offs in urban heat mitigation using a Bayesian Optimization framework for an urban canopy layer model ↗
To mitigate the challenges of climate change and intensifying heat stress in urban areas, local adaptation strategies are discussed and introduced in cities worldwide. To understand processes and potential trade-offs of these strategies a Bayesian optimization and surrogate modeling framework was employed to investigate urban parameter ranges of heat mitigation strategies with focus on three thermal metrics: daytime air temperature, Universal Thermal Climate Index (UTCI), and nighttime air temperature. Based on an urban street canyon configuration, it was shown that heat mitigation measures th…
- arXiv · Published · First archived
A dataset of one-dimensional idealized probabilistic fields ↗
Verification of probabilistic weather forecasts remains a crucial aspect of numerical weather prediction, as new AI-based models become more widely used alongside the more traditional physics-based ensemble forecasting systems that continue to be developed and improved. We present a first-of-its-kind idealized probabilistic dataset composed of one-dimensional cases aimed at analyzing the behavior and properties of verification methods for probabilistic forecasts and comparing their behavior. It covers a wide range of probabilistic cases, such as constant, localized events, gradients, fronts, n…
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Check each original source for its methods, release status, limitations, and supporting data. A repository announcement, a preprint, and a published study provide different kinds of evidence. SYMTRI’s subject classification helps discovery; it does not independently validate the source’s claims.
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